Curriculum Vitae

Scientific Society Offices

Publications

Lab

Teaching

Honors/Awards

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Teaching Activities

GRADUATE ACTIVITIES:

Major Advisor:

• Swapnali Sawant, joined laboratory March 2003-Graduated 12/06, dissertation entitled “development of anticancer marine cembranoids”.
• Sandeep Jain, joined the laboratory September 2005. Antiproliferative and P-gp-modulating sipholanes from the Red Sea sponge Callyspongia siphonella.
• Mudit Mudit, joined August 2006. Design and synthesis of anti-invasive leads inspired by the Red Sea sponge Hemimycale arabica secondary metabolites.
• Ahmed Orabi, joined August 2006. Biocatalysis of palm oil g- and b-tocotrienols.
• Mohammad Khanfar, Joined June 2007. Preclinical development of anticancer marine natural products.
• Asmaa Sallam, joined laboratory January 2008. Investigation of marine bacteria Bacillus pumlus and Microlubifer species as sustained sources of anticancer secondary metabolites.
• Aladdin Alayoubi, joined June 2008. Enhancement of palm oil tocotrienols anticancer activity.

 

Committee Member:

• Harish Parihar 4/03-5/05 (graduated)
• Rahul Manek 4/03-5/05 (graduated)
• Jerry Nesamoy 4/03-8/05 (graduated)
• Ganesh Samant 4/05-5/07 (graduated)
• Amit Shridoe 5/06-Now

Journal Reviewer:

• Journal of Natural Products. More than 15 manuscripts reviewed over the past 4 years.
• Nutrition and Cancer.
• Journal of Herb, Spices, and Medicinal Plants.
• Natural Products Communication.

UNDERGRADUATE RESEARCH ACTIVITIES

Presentations:

1. Joshua Miller, Paul Sylvester, Khalid El Sayed, 2003. “Biocatalysis studies of palm oil a-tocopherol and a-tocotrienol”. 30^th MALTO Medicinal Chemistry-Pharmacognosy Meeting, Little Rock, Arkansas. May 2003.
2. Samir Yacoub, Khalid El Sayed, 2003. “Chemical transformation studies of mitraphylline and uncarine C, the major Cat’s Claw alkaloids”. 30^th MALTO Medicinal Chemistry-Pharmacognosy Meeting, Little Rock, Arkansas May 2003.
3. Joshua Miller, Paul Sylvester, Khalid El Sayed, 2003. “Biocatalysis studies of palm oil a-tocopherol and a-tocotrienol”. 3^rd Student Research Symposium, ULM, Monroe, LA, April 2, 2003.
4. Raghda Elsayed, Khalid El Sayed, and Fred Rainey. 2004 “Bioactive aromatic nitrogenated secondary metabolites from the marine derived bacterium Bacillus cereus”. 4^th Student Research Symposium, ULM, Monroe, LA, April, 2004.
5. Samir Yacoub, Khalid El Sayed, Fathi Halaweish, and E. Huntimer. 2004 “Chemical and microbial transformation studies of the bioactive marine natural products sipholane triterpenes”. 4^th Student Research Symposium, ULM, Monroe, LA, April 2004. (Best Undergraduate Poster Award).
6. Ashley Barbo, Swapnali Sawant, Diaa Youssef, and El Sayed, K. Latrunculins revisited: New semisynthetic bioactive latrunculins. 5^th Annual Student Research Symposium, ULM, Monroe, LA, April 2005 (Second place winner, Undergraduate student poster).
7. Mark McBride, Theresa McBride, and El Sayed, K.  Bioconversion Studies of the Bioactive Marine Sesterterpene Palinurin. 5^th Annual Student Research Symposium, ULM, Monroe, LA, April 2005 (Second place winner, Undergraduate student poster).
8. Boakye E., Bagaley, D., Rainey, F., El Sayed, K.  Novel Anticancer Phenazines from the Symbiotic Marine Actinomycete Pelagiobacter Species. 6^th ULM Student Research Symposium, April 26, 2006.
9. Prestridge, J., Yousaf, M., Wali, V., Sylvester, P., El Sayed, K., Steffen, R., Mueller, W. Semisynthetic studies of the anticancer tobacco cembranoids. North Louisiana Partnership for Innovation Regional Research Day, Shreveport, Louisiana, May 1, 2006.
10. Dalia Abdelhalim, Anne Hebert, A. Muralidharan, Shibu Thomas, Girish Shah, and Khalid El Sayed. Biocatalytic study of tobacco cembranoid (1S,2E,4R,6R,-7E,11E)-2,7,11-cembratriene-4,6-diol. ULM 7^th Annual Student Research Symposium. April 18, 2007, Monroe, Louisiana. (Best Undergraduate Poster Award).
11. Sadegh Ramezani, Amit Shirode, Vikram Wali, Girish Shah, Paul Sylvester, and Khalid El Sayed. Biocatalytic study of tobacco cembranoid (1S,2E,4S,6R,-7E,11E)-2,7,11-cembratriene-4,6-diol-6-O-acetate. The 34^th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 20-22, 2007, Monroe, Louisiana.
12. Justin Prestridge, Anbalagan Muralidharan, Amit Shirode, Shibu Thomas, Vikram Wali, Girish Shah, Paul Sylvester, and Khalid El Sayed Semisynthetic studies of the anticancer tobacco cembranoids. The 34^th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 20-22, 2007, Monroe, Louisiana.

Emerging Scholars Program Advisor:

1. Joshua Miller, Fall 2003.
2. John Meyer, Spring 2004.
3. Raghda Elsayed, Fall 2004.
4. Mark Mcbride, Spring 2005
5. Rebekah Brode, Fall 2005
6. Rebekah Brode, Spring 2006 (Student Withdrawn ESP for personal reasons)
7. Rebekah Brode, Fall 2006
8. Ellison, Lauren, Fall 2006
9. Ramezani Sadegh, Spring 2007
10. Ramezani Sadegh, Fall 2007

Teaching Elective Pharmacy 465 (Selected Medicinal Chemistry Research Topics) for Professional Students

1. Raghda El Sayed: Spring 2004, Bioactive aromatic nitrogenated secondary metabolites from the marine derived bacterium Bacillus cereus.
2. Ashley Barbo: Spring 2005, New semisynthetic bioactive latrunculins. (Coauthored a published paper).
3. Justin Prestridge: Spring 2006, Semisynthetic transformation of major tobacco cembranoid a-diol. (Coauthored a 2007 Plata Medica paper)
4. Boakye Ebenezer, Spring 2006, Novel Anticancer Phenazines from the Symbiotic Marine Actinomycete Pelagiobacter Species.
5. Anne Hebert, Summer 2006, Biocatalysis of minor tobacco cembranoid b-diol using symbiotic bacteria. (Coauthored a 2008 Biorg. Med Chem. paper )
6. Paige Newman, Spring 2007, Optimization of anti-invasive marine amcrolide latrunculin A using semisynthetic methods.
7. Dalia Abdelhalim, Spring 2007, Biocatalysis of the marine cembranoids sarcophine and 2-epi-16-deoxysarcophine using marine bacteria.
8. Pratik Shah, Fall 2007, Optimization of mutant marine actinomycete Pelagiobacter strains as a source of novel anticancer phenazine esters.
9. Dalia Abdelhalim, Spring 2008, Rationale design of anti-invasive tobacco cembranoids.
10. Joseph LeBlanc, Summer 2008, Preparation of water soluble prodrugs and stability studies of the anti-invasive drug leads PMH.